Risk of death from

major diseases

Aging is a multifactorial process that drives many severe diseases

Aging also damages many essential systems throughout our bodies

Functional deficits of aging

Declining sensory function, including vision, hearing, and smell, robs individuals of their independence in activities of daily living and can lead to social isolation, a major driver of depression and morbidity in the elderly.

Declines in innate and adaptive immunity increase the risk of hospitalization and death from a wide range of infections, including COVID-19, influenza, and pneumonia. Immune impairment also decreases the efficacy of vaccines in the elderly.

Persistent low-grade inflammation induced by an overactive alert system obstructs immune function while exacerbating cardiovascular disease and other late-life illnesses, increasing the risk of multiple morbidities, frailty, and premature death.

Impaired brain function interferes with activities of daily living, driving loss of mobility, independence, and quality of life. Cognitive impairment further diminishes health and well-being by interfering with management of chronic diseases.

Loss of muscle mass and strength with aging decreases energy and mobility and is a major cause of disability and frailty. Sarcopenia compounds the risk of falls, the principal cause of accidental death among the elderly.

Better healthcare has increased our life expectancy - but these gains are often accompanied by decreased quality of life

79 Life expectancy
63 Healthy life expectancy

We can do better: many people live past 100 in exceptional health

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Robert Marchand set a Guinness World Record as the oldest competitive cyclist at age 105.

He lived to be 109.

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Leila Denmark was a practicing pediatrician until age 103.

She lived to be 114.

BioAge is focused on deciphering the

molecular mechanisms that increase human

healthspan and lifespan

BioAge is focused on deciphering the

molecular mechanisms that increase

human healthspan and lifespan

BioAge is focused on

deciphering the molecular

mechanisms that increase

human healthspan and

lifespan

What would you do with more healthy time?

What would you do with more

healthy time?

What would you do with

more healthy time?

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