Pipeline
We are harnessing the biology of human aging to develop new therapies for metabolic diseases
We are harnessing the biology of human aging to develop new therapies for metabolic diseases
Program
Mechanism of Action
Target dosing
Indication
Status
BGE - 102
NLRP3
(CNS penetrant)
(CNS penetrant)
NLRP3 inhibitor
(CNS penetrant)
(CNS penetrant)
Oral QD
Obesity
IND-enabling
Discoverу
Lead Op
IND-enabling
Ph 1
Ph 2
Ph 3
Lead Op
Discoverу
Lead Op
IND-enabling
Ph 1
Ph 2
Ph 3
APJ
APJ agonist
Oral QD
Obesity
Lead Op
Discoverу
Lead Op
IND-enabling
Ph 1
Ph 2
Ph 3
Program 1
Program 2
Target discovery
Undisclosed
Undisclosed
Multiple targets
-
-
-
Cardiometabolic (various)
Cardiometabolic (various)
-
Disc.
Discoverу
Lead Op
IND-enabling
Ph 1
Ph 2
Ph 3
Disc.
Discoverу
Lead Op
IND-enabling
Ph 1
Ph 2
Ph 3
Disc.
Discoverу
Lead Op
IND-enabling
Ph 1
Ph 2
Ph 3
Program
BGE - 102
NLRP3
(CNS penetrant)
Mechanism of Action
NLRP3 inhibitor
(CNS penetrant)
(CNS penetrant)
Route of administration
Oral QD
Indication
Obesity
Status
IND-enabling
Discoverу
Lead Op
IND-enabling
Ph 1
Ph 2
Ph 3
Mechanism of Action
NLRP3 inhibitor
(CNS penetrant)
(CNS penetrant)
Route of administration
Oral QD
Indication
Obesity
Status
Lead Op
Discoverу
Lead Op
IND-enabling
Ph 1
Ph 2
Ph 3
Program
APJ
Mechanism of Action
APJ agonist
Route of administration
Oral QD
Indication
Obesity
Status
Lead Op
Discoverу
Lead Op
IND-enabling
Ph 1
Ph 2
Ph 3
Program
Program 1
Program 2
Target discovery
Mechanism of Action
Undisclosed
Route of administration
-
Indication
Cardiometabolic (various)
Status
![]()
Disc.
Discoverу
Lead Op
IND-enabling
Ph 1
Ph 2
Ph 3
Mechanism of Action
Undisclosed
Route of administration
-
Indication
Cardiometabolic (various)
Status
![]()
Disc.
Discoverу
Lead Op
IND-enabling
Ph 1
Ph 2
Ph 3
Mechanism of Action
Multiple targets
Route of administration
-
Indication
-
Status
![]()
Disc.
Discoverу
Lead Op
IND-enabling
Ph 1
Ph 2
Ph 3
