Science

SLOWING AGING AND TREATING DISEASE

Science has now demonstrated that genetic and drug interventions that target aging directly can extend lifespan and healthspan, delaying the onset of multiple age-related diseases. We believe that targeting aging will be the most powerful way to decrease disease and increase quality of life in an aging population.

BIOBANKS: INSIGHTS FROM HUMAN DATA

At BIOAGE, we are mapping human aging from the ground up. We have forged partnerships with unique biobanks containing healthy human samples collected over decades that are paired with extensive follow-up records that include detailed future healthspan, lifespan, and disease outcomes. We are building deep molecular profiles of these samples, incorporating proteomics, metabolomics, and transcriptomics to identify the best drug targets for healthy aging.

THE BIOAGE PLATFORM: DISCOVERING TARGETABLE MECHANISMS THAT DRIVE AGING

Multiple molecular pathways independently impact longevity. BIOAGE’s data-driven map of human aging has identified a broad set of targetable mechanisms that will have a positive impact on human healthspan. We are currently advancing multiple targets through drug discovery programs.

MACHINE LEARNING TO MAP HUMAN AGING

At BIOAGE, our drug discovery platform is driven by our human data. We develop and apply tools from machine learning and artificial intelligence to integrate proteomic, metabolomic, transcriptomic, and genetic information from human studies of short vs long-lived individuals.